New Insights into the Role and Mechanism of Macrophage Migration Inhibitory Factor in Epinephelus awoara Infected with Vibrio alginolyticus

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چکیده

Background: The cytokine Macrophage migration inhibitory factor (MIF) is involved in inflammatory diseases. objective of the present study was to measure expression levels MIF tissues Epinephelus awoara (E. awoara). mRNA were investigated including spleen, liver, brain, head kidney, stomach, gill, heart, intestine and muscle E. awoara. Methods: In experiment, infected with V. alginolyticus then they analyzed by ELISA confirm MIF, TNF-α IL-1 many diseased fishes higher than those healthy fishes. Result: increased significantly treatment groups. Likewise, infections showed significant increases content intestine, respectively. There evidence that stimulates release TNF-á IL-1. results have potential perpetuate connected process infectious

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ژورنال

عنوان ژورنال: Indian Journal of Animal Research

سال: 2022

ISSN: ['0367-6722', '0976-0555']

DOI: https://doi.org/10.18805/ijar.bf-1571